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Kyren Williams

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In this Jan. 1, 2021, file photo, Notre Dame running back Kyren Williams (23) runs with the ball during the Rose Bowl NCAA college football game in Arlington, Texas. Offensive coordinator Tommy Rees has seen the offense come together behind quarterback Jack Coan, a grad transfer from Wisconsin, and preseason All-American candidates in running back Kyren Williams, tight end Michael Mayer, center Jarrett Patterson and guard Cain Madden, another grad transfer.

Tread lightly.

That’s going to be the advice you get from a lot of bettors for the first week of the college football season. Heck, I’m sure it’s advice I’ve both dispensed and followed in past years.

Not this year. I’m going to instead trust the work I’ve put in getting ready for the season over the last couple months and attack lines that remain off of my numbers.

After three plays to start the week (a fourth was canceled because of a date change and I’ve downgraded it to a lean here), I’ve got seven more on Saturday. Ten plays in this column is a lot for one week based on past norms, but it’s a new year.

Caution isn’t much fun anyway.

Find picks for all of Saturday’s game, though presented in a new format, below. Lines are the best currently available in Las Vegas on the chosen side. Picks are labeled with three separate confidence categories — plays, leans and guesses.

Big Games

Penn State +5 at Wisconsin, over/under: 50. There’s a compelling case to be made that both of these teams are buy-ons this year. Wisconsin’s offense shouldn’t be as maddeningly inconsistent with a high rate of returners, and much of Penn State’s terrible 4-5 campaign in 2020 was a result of bad luck and not poor underlying process. The Badgers are probably a little safer given some uncertainty on the Nittany Lions’ defense, but this line reflects that. Guess: Wisconsin -5.

Alabama -19.5 at Miami, over/under: 61.5. This is an excessively high line for what’s undoubtedly a matchup between two of the top 10 most talented teams in the nation. That being said, it’s hard to use a numerical argument for betting against the Crimson Tide when they shatter numerical expectations almost every single season. The coaching mismatch is also alarming as Manny Diaz hasn’t proven to be an above-average decision maker, let alone one who can match wits with Nick Saban. Guess: Miami +19.5.

Indiana +3.5 at Iowa, over/under: 46. The betting market almost always trends towards efficiency, but I can’t get past thinking the opening price of Iowa -5.5 was closer to the true price. I make the spread Iowa -6 and given some of its matchup advantages — namely the top-ranked defense in the country by SP+’s preseason projection against Indiana’s lack of explosive offense — the Hawkeyes may win easier than that. Lean: Iowa -3.5.

Georgia +3 vs. Clemson in Charlotte, over/under: 51. There’s been a lot of talk about Georgia’s rash of injuries and absences the last couple weeks, and yet this line keeps sliding in its direction. That’s a testament to how much talent coach Kirby Smart has assembled. The unavailability of Darnell Washington and Arik Gilbert are a hit to the Bulldogs, but they should be able to manage. They have more than enough to endure a couple secondary injuries. It goes against the norm of the last several years, but for this season, Georgia has a better roster than Clemson. Lean: Georgia +3.

LSU -3 at UCLA, over/under: 65.5. Georgia would have been a play at anything above 3 — and so would UCLA. Luckily, I already locked in UCLA +4.5 over the summer but I’ll pick everything against current prices here. The Bruins still have a great chance to win outright, especially given their strength up front that could equalize or even best the Tigers in the trenches. UCLA didn’t even have to show much to beat Hawaii 44-10 last week, as it surely has some twists stashed away for LSU. Lean: UCLA +3.

Notre Dame -7 at Florida State, over/under: 56. Everyone is calling for a Notre Dame decline, and coming from a College Football Playoff appearance a year ago, it makes sense. But decline this much? Unlikely. The Seminoles have been a mediocre-at-best Power Five conference team over the last three seasons. They’re not recruiting at the same level as they once were and will be at disadvantages to the Irish all over the field. Play: Notre Dame -7.

Louisville +10.5 vs. Ole Miss in Atlanta, over/under: 76. Here’s the second big-time battle of two bet-on teams of the week. Ole Miss’ offense should be as electric as advertised behind quarterback Matt Corral, but Louisville has firepower of its own with quarterback Malik Cunningham. The Cardinals also have a defensive edge, one that should help keep this close throughout. Play: Louisville +10.5.

Big Plays

Marshall -2 at Navy, over/under: 47. The Thundering Herd are breaking in new coach Charles Huff, but there’s no reason to believe they’ll regress significantly under the former Alabama and Penn State assistant. And they’d need to regress significantly in order for Navy to have a chance considering the Midshipmen were at -1.5 net yards per play last year as opposed to the Herd’s +1.1 net yard per play. Play: Marshall -2.

West Virginia -3 at Maryland, over/under: 57.5. West Virginia broke out last year behind what was quietly one of the nation’s stingiest defenses, but almost everyone from that defense has now departed. Maryland is stacked with explosive players on offense, led by quarterback Taulia Tagovailoa, that should take advantage of a green opposing unit. Play: Maryland +3.

Louisiana Tech +22.5 at Mississippi State, over/under: 52.5. Louisiana Tech had no business posting a winning record last season — they pulled off two miracle wins to get to 4-3 — and now have been weakened by a number of players hitting the transfer portal. This wouldn’t have been a play at the opening price of -27, but the number has moved too far towards an underrated Mississippi State side. Play: Mississippi State -22.5.

UNR +3 at California, over/under: 52.5. Wolf Pack quarterback Carson Strong is deserving of all the praise he’s been given, but he doesn’t have enough around him. The Bears are a more complete team, one poised for a bounce-back year behind a defensive front that will harass Strong. Play: Cal -3.

UTSA +5.5 at Illinois, over/under: 49. The only thing that really separated Illinois from Nebraska in its 30-22 season-opening win was a 41-yard fumble return touchdown right before halftime. The Cornhuskers actually had a positive postgame win expectancy. Now the Illini are down to a backup quarterback in Arthur Sitkowski against a UTSA team on the rise after back-to-back big-time recruiting classes. Play: UTSA +5.5.

Other Picks

Lean: Texas -8 vs. Louisiana

Lean: Oklahoma -31.5 vs. Tulane

Lean: Kansas State -3 vs. Stanford (previously played at +2.5)

Lean: Temple +14.5 at Rutgers

Lean: Western Michigan +17 at Michigan

Lean: Baylor -13.5 at Texas State

Lean: Auburn -36.5 vs. Akron

Lean: Ohio +1.5 vs. Syracuse

Lean: Texas A&M -28.5 vs. Kent State

Lean: Washington State -16.5 vs. Utah State

Lean: Central Michigan +14.5 at Missouri

Guess: Fresno State +20.5 at Oregon

Guess: Miami (Ohio) +23 at Cincinnati

Guess: Florida Atlantic +23.5 at Florida

Guess: San Jose State +14.5 at USC

Guess: Arizona +12.5 vs. BYU

Guess: San Diego State -31 vs. New Mexico State

Guess: Northern Illinois +18.5 at Georgia Tech

Guess: South Alabama -1 vs. Southern Miss

Guess: Rice +19.5 at Arkansas

Guess: Pittsburgh -37.5 vs. Massachusetts

Guess: UL Monroe +31 at Kentucky

Guess: Texas Tech -1 vs. Houston

Guess: Army +2.5 at Georgia State

Guess: Oregon State +7 at Purdue

Case Keefer can be reached at 702-948-2790 or [email protected]. Follow Case on Twitter at twitter.com/casekeefer.

Article written by #LasVegasSun

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